Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress

Developing oligodendrocytes (OLs) are highly vulnerable to excitotoxicity and oxidative stress, both of which are important in the pathogenesis of many brain disorders. OL excitotoxicity is mediated by ionotropic glutamate receptors (iGluRs) of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic aci...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Deng, Wenbin, Wang, Hong, Rosenberg, Paul A., Volpe, Joseph J., Jensen, Frances E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419678/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15136737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307850101
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