The Chromatin Assembly Factor 1 Promotes Rad51-Dependent Template Switches at Replication Forks by Counteracting D-Loop Disassembly by the RecQ-Type Helicase Rqh1

At blocked replication forks, homologous recombination mediates the nascent strands to switch template in order to ensure replication restart, but faulty template switches underlie genome rearrangements in cancer cells and genomic disorders. Recombination occurs within DNA packaged into chromatin th...

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Detalhes bibliográficos
Main Authors: Pietrobon, Violena, Fréon, Karine, Hardy, Julien, Costes, Audrey, Iraqui, Ismail, Ochsenbein, Françoise, Lambert, Sarah A.E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196752/
https://ncbi.nlm.nih.gov/pubmed/25313826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001968
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