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Concerted Dynamic Motions of an FABP4 Model and Its Ligands Revealed by Microsecond Molecular Dynamics Simulations

[Image: see text] In this work, we investigate the dynamic motions of fatty acid binding protein 4 (FABP4) in the absence and presence of a ligand by explicitly solvated all-atom molecular dynamics simulations. The dynamics of one ligand-free FABP4 and four ligand-bound FABP4s is compared via multip...

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書誌詳細
主要な著者: Li, Yan, Li, Xiang, Dong, Zigang
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196735/
https://ncbi.nlm.nih.gov/pubmed/25231537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500374t
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