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Expansion of CAG Repeats in Escherichia coli Is Controlled by Single-Strand DNA Exonucleases of Both Polarities

The expansion of CAG·CTG repeat tracts is responsible for several neurodegenerative diseases, including Huntington disease and myotonic dystrophy. Understanding the molecular mechanism of CAG·CTG repeat tract expansion is therefore important if we are to develop medical interventions limiting expans...

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Bibliografske podrobnosti
Main Authors: Jackson, Adam, Okely, Ewa A., Leach, David R. F.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196609/
https://ncbi.nlm.nih.gov/pubmed/25081568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.168245
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