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TorsinA in the nuclear envelope

Early-onset torsion dystonia, a CNS-based movement disorder, is usually associated with a single amino acid deletion (ΔE302/303) in the protein torsinA. TorsinA is an AAA+ ATPase in the endoplasmic reticulum, but what it does is unknown. Here, we use torsinA mutants with defects in ATP hydrolysis (E...

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Bibliografische gegevens
Hoofdauteurs: Naismith, Teresa V., Heuser, John E., Breakefield, Xandra O., Hanson, Phyllis I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC419654/
https://ncbi.nlm.nih.gov/pubmed/15136718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308760101
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