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LULL1 Retargets TorsinA to the Nuclear Envelope Revealing an Activity That Is Impaired by the DYT1 Dystonia Mutation

TorsinA (TorA) is an AAA+ ATPase in the endoplasmic reticulum (ER) lumen that is mutated in early onset DYT1 dystonia. TorA is an essential protein in mice and is thought to function in the nuclear envelope (NE) despite localizing throughout the ER. Here, we report that transient interaction of TorA...

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Detalhes bibliográficos
Main Authors: Vander Heyden, Abigail B., Naismith, Teresa V., Snapp, Erik L., Hodzic, Didier, Hanson, Phyllis I.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688546/
https://ncbi.nlm.nih.gov/pubmed/19339278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0094
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