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LULL1 Retargets TorsinA to the Nuclear Envelope Revealing an Activity That Is Impaired by the DYT1 Dystonia Mutation

TorsinA (TorA) is an AAA+ ATPase in the endoplasmic reticulum (ER) lumen that is mutated in early onset DYT1 dystonia. TorA is an essential protein in mice and is thought to function in the nuclear envelope (NE) despite localizing throughout the ER. Here, we report that transient interaction of TorA...

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Detaylı Bibliyografya
Asıl Yazarlar: Vander Heyden, Abigail B., Naismith, Teresa V., Snapp, Erik L., Hodzic, Didier, Hanson, Phyllis I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Cell Biology 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688546/
https://ncbi.nlm.nih.gov/pubmed/19339278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-01-0094
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