The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein

Ubiquitin-(Ub) like proteins (Ubls) are conjugated to their targets by an enzymatic cascade involving an E1 activating enzyme, an E2 conjugating enzyme, and in some cases an E3 ligase. ISG15 is a Ubl that is conjugated to cellular proteins after IFN-α/β stimulation. Although the E1 enzyme for ISG15...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Zhao, Chen, Beaudenon, Sylvie L., Kelley, Melissa L., Waddell, M. Brett, Yuan, Weiming, Schulman, Brenda A., Huibregtse, Jon M., Krug, Robert M.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2004
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15131269/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402528101
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