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Fluticasone Induces Epithelial Injury and Alters Barrier Function in Normal Subjects

OBJECTIVE: The airway epithelium has a number of roles pivotal to the pathogenesis of asthma, including provision of a physical and immune barrier to the inhaled environment. Dysregulated injury and repair responses in asthma result in loss of airway epithelial integrity. Inhaled corticosteroids are...

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Detalhes bibliográficos
Main Authors: MacRedmond, Ruth E., Singhera, Gurpreet K., Wadsworth, Samuel J., Attridge, Susan, Bahzad, Mohammed, Williams, Kristy, Coxson, Harvey O., White, Steven R., Dorscheid, Delbert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196246/
https://ncbi.nlm.nih.gov/pubmed/25324978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7536.1000134
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