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Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke

The toll-like receptors (TLRs) are a key component of host defense in the respiratory epithelium. Cigarette smoking is associated with increased susceptibility to infection, while COPD is characterised by bacterial colonisation and infective exacerbations. We found reduced TLR4 gene expression in th...

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Detalhes bibliográficos
Main Authors: MacRedmond, Ruth E, Greene, Catherine M, Dorscheid, Delbert R, McElvaney, Noel G, O'Neill, Shane J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194695/
https://ncbi.nlm.nih.gov/pubmed/18034897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-84
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