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Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke
The toll-like receptors (TLRs) are a key component of host defense in the respiratory epithelium. Cigarette smoking is associated with increased susceptibility to infection, while COPD is characterised by bacterial colonisation and infective exacerbations. We found reduced TLR4 gene expression in th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2194695/ https://ncbi.nlm.nih.gov/pubmed/18034897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-8-84 |
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