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Genome coverage and sequence fidelity of φ29 polymerase-based multiple strand displacement whole genome amplification

Major efforts are underway to systematically define the somatic and germline genetic variations causally associated with disease. Genome-wide genetic analysis of actual clinical samples is, however, limited by the paucity of genomic DNA available. Here we have tested the fidelity and genome represen...

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Detalhes bibliográficos
Main Authors: Paez, J. Guillermo, Lin, Ming, Beroukhim, Rameen, Lee, Jeffrey C., Zhao, Xiaojun, Richter, Daniel J., Gabriel, Stacey, Herman, Paula, Sasaki, Hidefumi, Altshuler, David, Li, Cheng, Meyerson, Matthew, Sellers, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419624/
https://ncbi.nlm.nih.gov/pubmed/15150323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh069
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