Release of Ca(2+) from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells

Celastrol, a triterpene extracted from the Chinese “Thunder of God Vine”, is known to have anticancer activity, but its underlying mechanism is not completely understood. In this study, we show that celastrol kills several breast and colon cancer cell lines by induction of paraptosis, a cell death m...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Yoon, Mi Jin, Lee, A Reum, Jeong, Soo Ah, Kim, You-Sun, Kim, Jin Yeop, Kwon, Yong-Jun, Choi, Kyeong Sook
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196165/
https://ncbi.nlm.nih.gov/pubmed/25149175
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars