DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling

Dermatopontin (DPT), a tyrosine-rich, acidic matricellular protein, has been implicated in several human cancers. However, its biological functions and molecular mechanisms in cancer progression, particular hepatocellular carcinoma (HCC), remain unknown. We demonstrated that DPT was significantly do...

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Autores principales: Fu, Ying, Feng, Ming-Xuan, Yu, Jian, Ma, Ming-Ze, Liu, Xiao-Jin, Li, Jun, Yang, Xiao-Mei, Wang, Ya-Hui, Zhang, Yan-Li, Ao, Jun-Ping, Xue, Feng, Qin, Wenxin, Gu, Jianren, Xia, Qiang, Zhang, Zhi-Gang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196157/
https://ncbi.nlm.nih.gov/pubmed/25149533
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