DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling

Dermatopontin (DPT), a tyrosine-rich, acidic matricellular protein, has been implicated in several human cancers. However, its biological functions and molecular mechanisms in cancer progression, particular hepatocellular carcinoma (HCC), remain unknown. We demonstrated that DPT was significantly do...

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Detalhes bibliográficos
Main Authors: Fu, Ying, Feng, Ming-Xuan, Yu, Jian, Ma, Ming-Ze, Liu, Xiao-Jin, Li, Jun, Yang, Xiao-Mei, Wang, Ya-Hui, Zhang, Yan-Li, Ao, Jun-Ping, Xue, Feng, Qin, Wenxin, Gu, Jianren, Xia, Qiang, Zhang, Zhi-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196157/
https://ncbi.nlm.nih.gov/pubmed/25149533
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