Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma

Tumor-angiogenesis is the multi-factorial process of sprouting of endothelial cells (EC) into micro-vessels to provide tumor cells with nutrients and oxygen. To explore miRNAs as therapeutic angiogenesis-inhibitors, we performed a functional screen to identify miRNAs that are able to decrease EC via...

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Main Authors: Babae, Negar, Bourajjaj, Meriem, Liu, Yijia, Van Beijnum, Judy R., Cerisoli, Francesco, Scaria, Puthupparampil V., Verheul, Mark, Van Berkel, Maaike P., Pieters, Ebel H. E., Van Haastert, Rick J., Yousefi, Afrouz, Mastrobattista, Enrico, Storm, Gert, Berezikov, Eugene, Cuppen, Edwin, Woodle, Martin, Schaapveld, Roel Q. J., Prevost, Gregoire P., Griffioen, Arjan W., Van Noort, Paula I., Schiffelers, Raymond M.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2014
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196156/
https://ncbi.nlm.nih.gov/pubmed/25149532
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