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Microfluidic device reads up to four consecutive base pairs in DNA sequencing-by-synthesis

We have developed the first fully integrated microfluidic system for DNA sequencing-by-synthesis. Using this chip and fluorescence detection, we have reliably sequenced up to 4 consecutive bps. The described sequencer can be integrated with other microfluidic components on the same chip to produce t...

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Detalhes bibliográficos
Main Authors: Kartalov, Emil P., Quake, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419614/
https://ncbi.nlm.nih.gov/pubmed/15155856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh613
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