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Frequency of gaps observed in a structurally aligned protein pair database suggests a simple gap penalty function
Gap penalty is an important component of the scoring scheme that is needed when searching for homologous proteins and for accurate alignment of protein sequences. Most homology search and sequence alignment algorithms employ a heuristic ‘affine gap penalty’ scheme q + r × n, in which q is the penalt...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419611/ https://ncbi.nlm.nih.gov/pubmed/15155852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh610 |
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