BDNF-TrkB signaling through Erk1/2(MAPK) phosphorylation mediates the enhancement of fear memory induced by glucocorticoids

Activation of glucocorticoid receptors (GR) by glucocorticoid hormones (GC) enhances contextual fear memories through the activation of the Erk1/2(MAPK) signaling pathway. However, the molecular mechanism mediating this effect of GC remains unknown. Here we used complementary molecular and behaviora...

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Main Authors: Revest, J-M, Le Roux, A, Roullot-Lacarrière, V, Kaouane, N, Vallée, M, Kasanetz, F, Rougé-Pont, F, Tronche, F, Desmedt, A, Piazza, P V
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195976/
https://ncbi.nlm.nih.gov/pubmed/24126929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.134
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