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The calcium-dependent ribonuclease XendoU promotes ER network formation through local RNA degradation

How cells shape and remodel organelles in response to cellular signals is a poorly understood process. Using Xenopus laevis egg extract, we found that increases in cytosolic calcium lead to the activation of an endogenous ribonuclease, XendoU. A fraction of XendoU localizes to the endoplasmic reticu...

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Autori principali: Schwarz, Dianne S., Blower, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195833/
https://ncbi.nlm.nih.gov/pubmed/25287301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406037
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