TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis

Compartmentalization of Toll-like receptors (TLRs) in intestinal epithelial cells (IECs) regulates distinct immune responses to microbes; however, the specific cellular machinery that controls this mechanism has not been fully identified. Here we provide genetic evidences that the recycling endosoma...

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Autors principals: Yu, Shiyan, Nie, Yingchao, Knowles, Byron, Sakamori, Ryotaro, Stypulkowski, Ewa, Patel, Chirag, Das, Soumyashree, Douard, Veronique, Ferraris, Ronaldo P, Bonder, Edward M, Goldenring, James R, Ip, Yicktung Tony, Gao, Nan
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195784/
https://ncbi.nlm.nih.gov/pubmed/25063677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201487888
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