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Molecular changes in neurons in multiple sclerosis: Altered axonal expression of Na(v)1.2 and Na(v)1.6 sodium channels and Na(+)/Ca(2)+ exchanger

Although voltage-gated sodium channels are known to be deployed along experimentally demyelinated axons, the molecular identities of the sodium channels expressed along axons in human demyelinating diseases such as multiple sclerosis (MS) have not been determined. Here we demonstrate changes in the...

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Détails bibliographiques
Auteurs principaux: Craner, Matthew J., Newcombe, Jia, Black, Joel A., Hartle, Caroline, Cuzner, M. Louise, Waxman, Stephen G.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC419575/
https://ncbi.nlm.nih.gov/pubmed/15148385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402765101
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