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Voltage-gated sodium channel Na(v)1.5 contributes to astrogliosis in an in vitro model of glial injury via reverse Na(+)/Ca(2+) exchange

Astrogliosis is a prominent feature of many, if not all, pathologies of the brain and spinal cord, yet a detailed understanding of the underlying molecular pathways involved in the transformation from quiescent to reactive astrocyte remains elusive. We investigated the contribution of voltage-gated...

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Autori principali: Pappalardo, Laura W., Samad, Omar A., Black, Joel A., Waxman, Stephen G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060891/
https://ncbi.nlm.nih.gov/pubmed/24740847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22671
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