Population pharmacokinetics of quinine in pregnant women with uncomplicated Plasmodium falciparum malaria in Uganda

OBJECTIVES: Oral quinine is used for the treatment of uncomplicated malaria during pregnancy, but few pharmacokinetic data are available for this population. Previous studies have reported a substantial effect of malaria on the pharmacokinetics of quinine resulting from increased α-1-acid glycoprote...

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Autors principals: Kloprogge, Frank, Jullien, Vincent, Piola, Patrice, Dhorda, Mehul, Muwanga, Sulaiman, Nosten, François, Day, Nicholas P. J., White, Nicholas J., Guerin, Philippe J., Tarning, Joel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195470/
https://ncbi.nlm.nih.gov/pubmed/24970740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku228
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