Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging

Aging is thought to be caused by the accumulation of damage, primarily from oxidative modifications of cellular components by reactive oxygen species (ROS). Here we used yeast methionine sulfoxide reductases MsrA and MsrB to address this hypothesis. In the presence of oxygen, these antioxidants coul...

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Detaylı Bibliyografya
Asıl Yazarlar: Koc, Ahmet, Gasch, Audrey P., Rutherford, Julian C., Kim, Hwa-Young, Gladyshev, Vadim N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2004
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC419546/
https://ncbi.nlm.nih.gov/pubmed/15141092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307929101
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