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Internalizing cancer antibodies from phage libraries selected on tumor cells and yeast displayed tumor antigens

A number of approaches have been utilized to generate antibodies to cancer cell surface receptors which can be used as potential therapeutics. A number of these therapeutic approaches, including antibody-drug conjugates, immunotoxins, and targeted nucleic acid delivery, require antibodies that not o...

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Detalhes bibliográficos
Main Authors: Zhou, Yu, Zou, Hao, Zhang, Shaoyi, Marks, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4195448/
https://ncbi.nlm.nih.gov/pubmed/20851130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.09.006
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