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Concentration-dependent regulation of thyrotropin receptor function by thyroid-stimulating antibody
Thyrotropin receptor (TSHR) Ab’s of the stimulating variety are the cause of hyperthyroid Graves disease. MS-1 is a hamster mAb with TSHR-stimulating activity. To examine the in vivo biological activity of MS-1, mice were treated with purified MS-1 intraperitoneally and the thyroid response evaluate...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419493/ https://ncbi.nlm.nih.gov/pubmed/15173885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421334 |
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