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RNAi-mediated silencing of TEL/AML1 reveals a heat-shock protein— and survivin–dependent mechanism for survival
The TEL/AML1 fusion gene results from the most frequent t(12;21)(p13;q22) translocation in childhood acute lymphoblastic leukemia (ALL). Its contribution to transformation is largely unknown, in particular with respect to survival and apoptosis. We therefore silenced TEL/AML1 expression in leukemic...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194423/ https://ncbi.nlm.nih.gov/pubmed/17095626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-019612 |
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