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Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution

Age-associated thymic involution results in diminished T cell output and function in aged individuals. However, molecular mediators contributing to the decline in thymic function during early thymic involution remain largely unknown. Here we present transcriptional profiling of purified thymic strom...

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Main Authors: Ki, Sanghee, Park, Daechan, Selden, Hilary J., Seita, Jun, Chung, Haewon, Kim, Jonghwan, Iyer, Vishwanath R., Ehrlich, Lauren I. R.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194175/
https://ncbi.nlm.nih.gov/pubmed/25284794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.070
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