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Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution

Age-associated thymic involution results in diminished T cell output and function in aged individuals. However, molecular mediators contributing to the decline in thymic function during early thymic involution remain largely unknown. Here we present transcriptional profiling of purified thymic strom...

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Detalhes bibliográficos
Main Authors: Ki, Sanghee, Park, Daechan, Selden, Hilary J., Seita, Jun, Chung, Haewon, Kim, Jonghwan, Iyer, Vishwanath R., Ehrlich, Lauren I. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194175/
https://ncbi.nlm.nih.gov/pubmed/25284794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.070
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