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mir33 Inhibition Overcomes Deleterious Effects of Diabetes on Atherosclerosis Plaque Regression in Mice

RATIONALE: Diabetes increases cardiovascular disease risk in humans and remains elevated despite cholesterol-lowering therapy with statins. Consistent with this, in mouse models diabetes impairs atherosclerosis plaque regression after aggressive cholesterol-lowering. miR33 is a key negative regulato...

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Detalhes bibliográficos
Main Authors: Distel, Emilie, Barrett, Tessa J., Chung, Kellie, Girgis, Natasha M., Parathath, Saj, Essau, Christine C., Murphy, Andrew J., Moore, Kathryn J., Fisher, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194153/
https://ncbi.nlm.nih.gov/pubmed/25201910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.304164
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