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Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer
Tumour cells sustain their high proliferation rate through metabolic reprogramming, whereby cellular metabolism shifts from oxidative phosphorylation to aerobic glycolysis, even under normal oxygen levels. Hypoxia-inducible factor 1A (HIF1A) is a major regulator of this process, but its activation u...
Gorde:
Egile Nagusiak: | , , , , , , , , , , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
BlackWell Publishing Ltd
2014
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194125/ https://ncbi.nlm.nih.gov/pubmed/24837709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201386874 |
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