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Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

Tumour cells sustain their high proliferation rate through metabolic reprogramming, whereby cellular metabolism shifts from oxidative phosphorylation to aerobic glycolysis, even under normal oxygen levels. Hypoxia-inducible factor 1A (HIF1A) is a major regulator of this process, but its activation u...

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מידע ביבליוגרפי
Main Authors: Zecchini, Vincent, Madhu, Basetti, Russell, Roslin, Pértega-Gomes, Nelma, Warren, Anne, Gaude, Edoardo, Borlido, Joana, Stark, Rory, Ireland-Zecchini, Heather, Rao, Roheet, Scott, Helen, Boren, Joan, Massie, Charlie, Asim, Mohammad, Brindle, Kevin, Griffiths, John, Frezza, Christian, Neal, David E, Mills, Ian G
פורמט: Artigo
שפה:Inglês
יצא לאור: BlackWell Publishing Ltd 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194125/
https://ncbi.nlm.nih.gov/pubmed/24837709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201386874
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