Fip1 regulates mRNA alternative polyadenylation to promote stem cell self-renewal

mRNA alternative polyadenylation (APA) plays a critical role in post-transcriptional gene control and is highly regulated during development and disease. However, the regulatory mechanisms and functional consequences of APA remain poorly understood. Here, we show that an mRNA 3′ processing factor, F...

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Autores principales: Lackford, Brad, Yao, Chengguo, Charles, Georgette M, Weng, Lingjie, Zheng, Xiaofeng, Choi, Eun-A, Xie, Xiaohui, Wan, Ji, Xing, Yi, Freudenberg, Johannes M, Yang, Pengyi, Jothi, Raja, Hu, Guang, Shi, Yongsheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4194112/
https://ncbi.nlm.nih.gov/pubmed/24596251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386537
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