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Transformation resistance in a premature aging disorder identifies a tumor-protective function of BRD4
Advanced age and DNA damage accumulation are strong risk factors for cancer. The premature-aging disorder Hutchinson Gilford Progeria Syndrome (HGPS) provides a unique opportunity to study the interplay between DNA damage and aging- associated tumor mechanisms, since HGPS patients do not develop tum...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194066/ https://ncbi.nlm.nih.gov/pubmed/25284786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.08.069 |
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