Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38

Macrophages contribute to tissue homeostasis and influence inflammatory responses by modulating their phenotype in response to the local environment. Understanding the molecular mechanisms governing this plasticity would open new avenues for the treatment for inflammatory disorders. We show that del...

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Hauptverfasser: Escolano, Amelia, Martínez-Martínez, Sara, Alfranca, Arántzazu, Urso, Katia, Izquierdo, Helena M, Delgado, Mario, Martín, Francisco, Sabio, Guadalupe, Sancho, David, Gómez-del Arco, Pablo, Redondo, Juan Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193919/
https://ncbi.nlm.nih.gov/pubmed/24596247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386369
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