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Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38

Macrophages contribute to tissue homeostasis and influence inflammatory responses by modulating their phenotype in response to the local environment. Understanding the molecular mechanisms governing this plasticity would open new avenues for the treatment for inflammatory disorders. We show that del...

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Detalhes bibliográficos
Main Authors: Escolano, Amelia, Martínez-Martínez, Sara, Alfranca, Arántzazu, Urso, Katia, Izquierdo, Helena M, Delgado, Mario, Martín, Francisco, Sabio, Guadalupe, Sancho, David, Gómez-del Arco, Pablo, Redondo, Juan Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193919/
https://ncbi.nlm.nih.gov/pubmed/24596247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386369
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