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Computational Modeling Reveals that a Combination of Chemotaxis and Differential Adhesion Leads to Robust Cell Sorting during Tissue Patterning

Robust tissue patterning is crucial to many processes during development. The "French Flag" model of patterning, whereby naïve cells in a gradient of diffusible morphogen signal adopt different fates due to exposure to different amounts of morphogen concentration, has been the most widely...

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Detalhes bibliográficos
Main Authors: Tan, Rui Zhen, Chiam, Keng-Hwee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193783/
https://ncbi.nlm.nih.gov/pubmed/25302949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109286
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