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Computational Modeling Reveals that a Combination of Chemotaxis and Differential Adhesion Leads to Robust Cell Sorting during Tissue Patterning

Robust tissue patterning is crucial to many processes during development. The "French Flag" model of patterning, whereby naïve cells in a gradient of diffusible morphogen signal adopt different fates due to exposure to different amounts of morphogen concentration, has been the most widely...

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Библиографические подробности
Главные авторы: Tan, Rui Zhen, Chiam, Keng-Hwee
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193783/
https://ncbi.nlm.nih.gov/pubmed/25302949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109286
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