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Gene and protein expression and cellular localisation of cytochrome P450 enzymes of the 1A, 2A, 2C, 2D and 2E subfamilies in equine intestine and liver

BACKGROUND: Among the cytochrome P450 enzymes (CYP), families 1–3 constitute almost half of total CYPs in mammals and play a central role in metabolism of a wide range of pharmaceuticals. This study investigated gene and protein expression and cellular localisation of CYP1A, CYP2A, CYP2C, CYP2D and...

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Bibliographic Details
Main Authors: Tydén, Eva, Tjälve, Hans, Larsson, Pia
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192735/
https://ncbi.nlm.nih.gov/pubmed/25288196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13028-014-0069-8
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