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Mitochondrial reactive oxygen species production and respiratory complex activity in rats with pressure overload-induced heart failure

We investigated the impact of cardiac reactive oxygen species (ROS) during the development of pressure overload-induced heart failure. We used our previously described rat model where transverse aortic constriction (TAC) induces compensated hypertrophy after 2 weeks, heart failure with preserved eje...

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Main Authors: Schwarzer, Michael, Osterholt, Moritz, Lunkenbein, Anne, Schrepper, Andrea, Amorim, Paulo, Doenst, Torsten
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192702/
https://ncbi.nlm.nih.gov/pubmed/24951621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.274704
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