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Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with Temozolomide

Inhibition of protein deacetylation enzymes, alone or in combination with standard chemotherapies, is an exciting addition to cancer therapy. We have investigated the effect of deacetylase inhibition on the metabolism of glioblastoma cells. (1)H NMR metabolomics analysis was used to determine the ma...

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Bibliografische gegevens
Hoofdauteurs: Cuperlovic-Culf, Miroslava, Touaibia, Mohamed, St-Coeur, Patrick-Denis, Poitras, Julie, Morin, Pier Jr, Culf, Adrian S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192694/
https://ncbi.nlm.nih.gov/pubmed/25222834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo4030807
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