Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages

Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication. The underlying molecular mechanisms involved remain largely unknown. In this study, we assessed ep...

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Bibliographic Details
Main Authors: Marr, Alexandra K., MacIsaac, Julia L., Jiang, Ruiwei, Airo, Adriana M., Kobor, Michael S., McMaster, W. Robert
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192605/
https://ncbi.nlm.nih.gov/pubmed/25299267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004419
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