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Impact of Leishmania Infection on Host Macrophage Nuclear Physiology and Nucleopore Complex Integrity

The protease GP63 is an important virulence factor of Leishmania parasites. We previously showed that GP63 reaches the perinuclear area of host macrophages and that it directly modifies nuclear translocation of the transcription factors NF-κB and AP-1. Here we describe for the first time, using mole...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Isnard, Amandine, Christian, Jan G., Kodiha, Mohamed, Stochaj, Ursula, McMaster, W. Robert, Olivier, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380401/
https://ncbi.nlm.nih.gov/pubmed/25826301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004776
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