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Structural Basis for the Recognition of Human Cytomegalovirus Glycoprotein B by a Neutralizing Human Antibody

Human cytomegalovirus (HCMV) infections are life-threating to people with a compromised or immature immune system. Upon adhesion, fusion of the virus envelope with the host cell is initiated. In this step, the viral glycoprotein gB is considered to represent the major fusogen. Here, we present for t...

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Détails bibliographiques
Auteurs principaux: Spindler, Nadja, Diestel, Uschi, Stump, Joachim D., Wiegers, Anna-Katharina, Winkler, Thomas H., Sticht, Heinrich, Mach, Michael, Muller, Yves A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192593/
https://ncbi.nlm.nih.gov/pubmed/25299639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004377
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