Structural Basis for the Recognition of Human Cytomegalovirus Glycoprotein B by a Neutralizing Human Antibody

Human cytomegalovirus (HCMV) infections are life-threating to people with a compromised or immature immune system. Upon adhesion, fusion of the virus envelope with the host cell is initiated. In this step, the viral glycoprotein gB is considered to represent the major fusogen. Here, we present for t...

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Main Authors: Spindler, Nadja, Diestel, Uschi, Stump, Joachim D., Wiegers, Anna-Katharina, Winkler, Thomas H., Sticht, Heinrich, Mach, Michael, Muller, Yves A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192593/
https://ncbi.nlm.nih.gov/pubmed/25299639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004377
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