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Detergent-Induced Stabilization and Improved 3D Map of the Human Heteromeric Amino Acid Transporter 4F2hc-LAT2

Human heteromeric amino acid transporters (HATs) are membrane protein complexes that facilitate the transport of specific amino acids across cell membranes. Loss of function or overexpression of these transporters is implicated in several human diseases such as renal aminoacidurias and cancer. HATs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Meury, Marcel, Costa, Meritxell, Harder, Daniel, Stauffer, Mirko, Jeckelmann, Jean-Marc, Brühlmann, Béla, Rosell, Albert, Ilgü, Hüseyin, Kovar, Karin, Palacín, Manuel, Fotiadis, Dimitrios
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192586/
https://ncbi.nlm.nih.gov/pubmed/25299125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109882
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