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Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

Heteromeric amino acid transporters (HATs) are the unique example, known in all kingdoms of life, of solute transporters composed of two subunits linked by a conserved disulfide bridge. In metazoans, the heavy subunit is responsible for the trafficking of the heterodimer to the plasma membrane, and...

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Autors principals: Rosell, Albert, Meury, Marcel, Álvarez-Marimon, Elena, Costa, Meritxell, Pérez-Cano, Laura, Zorzano, Antonio, Fernández-Recio, Juan, Palacín, Manuel, Fotiadis, Dimitrios
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939895/
https://ncbi.nlm.nih.gov/pubmed/24516142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323779111
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