Myosin Light Chain Kinase (MLCK) Regulates Cell Migration in a Myosin Regulatory Light Chain Phosphorylation-independent Mechanism

Myosin light chain kinase (MLCK) has long been implicated in the myosin phosphorylation and force generation required for cell migration. Here, we surprisingly found that the deletion of MLCK resulted in fast cell migration, enhanced protrusion formation, and no alteration of myosin light chain phos...

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Detalhes bibliográficos
Main Authors: Chen, Chen, Tao, Tao, Wen, Cheng, He, Wei-Qi, Qiao, Yan-Ning, Gao, Yun-Qian, Chen, Xin, Wang, Pei, Chen, Cai-Ping, Zhao, Wei, Chen, Hua-Qun, Ye, An-Pei, Peng, Ya-Jing, Zhu, Min-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192498/
https://ncbi.nlm.nih.gov/pubmed/25122766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567446
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