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Molecular Basis of Kindlin-2 Binding to Integrin-linked Kinase Pseudokinase for Regulating Cell Adhesion

Integrin-linked kinase (ILK) is a distinct intracellular adaptor essential for integrin-mediated cell-extracellular matrix adhesion, cell spreading, and migration. Acting as a major docking platform in focal adhesions, ILK engages many proteins to dynamically link integrins with the cytoskeleton, bu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fukuda, Koichi, Bledzka, Kamila, Yang, Jun, Perera, H. Dhanuja, Plow, Edward F., Qin, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192489/
https://ncbi.nlm.nih.gov/pubmed/25160619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596692
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