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Efficient Gene Targeting in Golden Syrian Hamsters by the CRISPR/Cas9 System
The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research. Here, we report the first successful application of the CRISPR/Cas9 system to efficientl...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4192357/ https://ncbi.nlm.nih.gov/pubmed/25299451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109755 |
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