The clinical response to vemurafenib in a patient with a rare BRAF(V600DK601del) mutation-positive melanoma

BACKGROUND: Mutations in the activation segment of the v-raf murine sarcoma viral oncogene homolog B (BRAF) gene are present in approximately 50% of melanomas. The selective BRAF inhibitor vemurafenib has demonstrated significant clinical benefits in patients with melanomas harboring the most common...

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Autores principales: Trudel, Stéphanie, Odolczyk, Norbert, Dremaux, Julie, Toffin, Jérôme, Regnier, Aline, Sevestre, Henri, Zielenkiewicz, Piotr, Arnault, Jean-Philippe, Gubler, Brigitte
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192296/
https://ncbi.nlm.nih.gov/pubmed/25265970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-727
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