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Acquired Resistance to Selective Estrogen Receptor Modulators (SERMs) in Clinical Practice (Tamoxifen & Raloxifene) by Selection Pressure in Breast Cancer Cell Populations

Tamoxifen, a pioneering selective estrogen receptor modulator (SERM), has long been a therapeutic choice for all stages of estrogen receptor (ER)-positive breast cancer. The clinical application of long-term adjuvant antihormone therapy for the breast cancer has significantly improved breast cancer...

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Bibliographic Details
Main Authors: Fan, Ping, Jordan, V. Craig
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192097/
https://ncbi.nlm.nih.gov/pubmed/24930824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.06.002
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